You cannot run Clip Studio Paint on both computers at the exact same time.

If you pay for Clip Studio Paint via a monthly or annual subscription plan, the multi-device rules are much simpler. Celsys offers specific tiered plans based on how many devices you need. Subscription Plan Tiers

Click to transfer the license to the new machine.

The you want to use (e.g., Windows desktop and iPad)

Downloading the software on two computers is only half the battle; you also need access to your work. Clip Studio Paint includes a built-in cloud service to seamlessly bridge your devices. Using the Clip Studio Cloud