Open the downloaded .exe or .dmg file. Do not connect the USB cable until prompted by the installer to avoid hardware recognition errors.

This is the recommended file for most users as it includes the scanner driver plus essential utilities like Brother Control Center 4 and Nuance PaperPort .

Follow the on-screen prompts to finish the installation. If you are on a Mac, you may need to add the scanner via the System Settings after the driver is installed. Available Software and Utilities

Follow these steps to set up your scanner on Windows, macOS, or Linux:

The ADS-2100e is compatible with a variety of productivity tools that can be downloaded individually or as part of a suite:

Navigate to the Brother Downloads Page and choose your operating system (e.g., Windows 11, macOS 14, or Linux).

For users of older operating systems or those who prefer alternative interfaces, VueScan provides reverse-engineered drivers that support the ADS-2100e without requiring official Brother software. Downloads | ADS-2100e | United Kingdom - Brother support

A dedicated utility from Brother to cleanly remove old driver versions before a fresh installation.