Check if your "Mute" toggle is on in the PSP system settings within Adrenaline.

Ensure your Adrenaline is updated to the latest version (6.0 or higher).

The game takes up roughly 1.6 GB of space. Ensure your Memory Card or microSD card has enough room.

Most Vita enthusiasts use the Adrenaline custom firmware plugin. This transforms your Vita into a fully functional PSP, allowing you to run ISO/CSO files of games you own. Enhancing the Experience on PS Vita

Use the "Camera Patch" or "Remastered Controls" plugins to further enhance the resolution and color depth. ⚡ Faster Load Times

Here is everything you need to know about getting Midnight Club 3 running on your PS Vita. The Legal Way: PS Store and Adrenaline

If you need help , mapping the second analog stick , or finding your old save files , let me know! I can walk you through the specific plugins you'll need to make the game look and play like a modern remaster.