Uniprot Download Fasta [new] Guide

Check individual boxes or select all results.

Use the left-hand sidebar to narrow results by organism, reviewed status (Swiss-Prot vs. TrEMBL), or length. uniprot download fasta

If you need the entire Swiss-Prot or TrEMBL database (gigabytes of data), use the UniProt FTP server. This is the preferred method for local BLAST database creation. Check individual boxes or select all results

Enter your query (e.g., "human kinase") in the search bar. reviewed status (Swiss-Prot vs. TrEMBL)

Select "FASTA (canonical)" or "FASTA (canonical & isoform)" depending on your research needs.

This guide covers every method to download FASTA files from UniProt, ranging from simple browser clicks to automated API scripts. 1. Downloading from the UniProt Website (Manual)